Check the driver quartering. One of the wheels is probably far enough out of quarter that you can see it. When the crankpins on one side are at the top of their travel, the other side should line up horizontally. You will have to completely dis-assemble the model to fix it, but you can probably twist the wheel into place by hand. I just did it 2 weeks ago to a 10-wheeler, without a quartering jig. Disconnect the piston rods completely, leaving just the rods connecting the drivers, and roll the mechanism by hand. When you feel the bind, you should see which wheel is out of quarter. If it can be turned by hand, just move it a little at a time until the bind is gone.
If it won't turn by hand you will need a wheel puller and quartering jig. Northwest Short Line makes them.
If it won't turn by hand you will need a wheel puller and quartering jig. Northwest Short Line makes them.